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High efficiency reduction capability for the formation of Fab׳ antibody fragments from F(ab)(2) units
Antibodies have widespread applications in areas ranging from therapeutics to chromatography and protein microarrays. Certain applications require only the fragment antigen-binding (Fab) units of the protein. This study compares the cleavage efficacy of dithiothreitol (DTT), mercaptoethylamine (MEA)...
Autores principales: | Crivianu-Gaita, Victor, Romaschin, Alexander, Thompson, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668623/ https://www.ncbi.nlm.nih.gov/pubmed/29124142 http://dx.doi.org/10.1016/j.bbrep.2015.04.004 |
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