Effect of methionine-35 oxidation on the aggregation of amyloid-β peptide

Aggregation of Aβ peptides into amyloid plaques is considered to trigger the Alzheimer’s disease (AD), however the mechanism behind the AD onset has remained elusive. It is assumed that the insoluble Aβ aggregates enhance oxidative stress (OS) by generating free radicals with the assistance of bound...

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Detalles Bibliográficos
Autores principales: Friedemann, Merlin, Helk, Eneken, Tiiman, Ann, Zovo, Kairit, Palumaa, Peep, Tõugu, Vello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668694/
https://www.ncbi.nlm.nih.gov/pubmed/29124171
http://dx.doi.org/10.1016/j.bbrep.2015.07.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668694/
https://www.ncbi.nlm.nih.gov/pubmed/29124171
http://dx.doi.org/10.1016/j.bbrep.2015.07.017

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