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Effect of methionine-35 oxidation on the aggregation of amyloid-β peptide
Aggregation of Aβ peptides into amyloid plaques is considered to trigger the Alzheimer’s disease (AD), however the mechanism behind the AD onset has remained elusive. It is assumed that the insoluble Aβ aggregates enhance oxidative stress (OS) by generating free radicals with the assistance of bound...
Autores principales: | Friedemann, Merlin, Helk, Eneken, Tiiman, Ann, Zovo, Kairit, Palumaa, Peep, Tõugu, Vello |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668694/ https://www.ncbi.nlm.nih.gov/pubmed/29124171 http://dx.doi.org/10.1016/j.bbrep.2015.07.017 |
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