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Oxidative stress-mediated antitumor activity of erythorbic acid in high doses

Intravenous (iv) infusion of high-dose ascorbic acid (AA) has been used as a treatment for cancer patients. The tumoricidal action of AA occurs due to its prooxidant effect. Erythorbic acid (EA), one of the AA epimers, has reduced vitamin C activity, while the antioxidant activity of EA is similar t...

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Detalles Bibliográficos
Autores principales: Miura, Kaori, Yazama, Futoshi, Tai, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668849/
https://www.ncbi.nlm.nih.gov/pubmed/29124174
http://dx.doi.org/10.1016/j.bbrep.2015.07.018