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Predicting CK2 beta-dependent substrates using linear patterns

CK2 is a constitutively active Ser/Thr protein kinase deregulated in cancer and other pathologies, responsible for about the 20% of the human phosphoproteome. The holoenzyme is a complex composed of two catalytic (α or α´) and two regulatory (β) subunits, with individual subunits also coexisting in...

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Detalles Bibliográficos
Autores principales: Núñez de Villavicencio-Díaz, Teresa, Mazola, Yuliet, Perera Negrín, Yasser, Cruz García, Yiliam, Guirola Cruz, Osmany, Perea Rodríguez, Silvio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668876/
https://www.ncbi.nlm.nih.gov/pubmed/29124183
http://dx.doi.org/10.1016/j.bbrep.2015.08.011