Conservation of structure and function in vertebrate c-FLIP proteins despite rapid evolutionary change

Cellular FLICE-like inhibitory protein (c-FLIP, gene symbol CFLAR) was first identified as a negative regulator of death receptor-mediated apoptosis in mammals. To understand the ubiquity and diversity of the c-FLIP protein subfamily during evolution, c-FLIP orthologs were identified from a comprehe...

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Detalles Bibliográficos
Autores principales: Sakamaki, Kazuhiro, Iwabe, Naoyuki, Iwata, Hiroaki, Imai, Kenichiro, Takagi, Chiyo, Chiba, Kumiko, Shukunami, Chisa, Tomii, Kentaro, Ueno, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668880/
https://www.ncbi.nlm.nih.gov/pubmed/29124180
http://dx.doi.org/10.1016/j.bbrep.2015.08.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668880/
https://www.ncbi.nlm.nih.gov/pubmed/29124180
http://dx.doi.org/10.1016/j.bbrep.2015.08.005

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