C-Terminal Truncated α-Synuclein Fibrils Contain Strongly Twisted β-Sheets

[Image: see text] C-terminal truncations of monomeric wild-type alpha-synuclein (henceforth WT-αS) have been shown to enhance the formation of amyloid aggregates both in vivo and in vitro and have been associated with accelerated progression of Parkinson’s disease (PD). The correlation with PD may n...

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Detalles Bibliográficos
Autores principales: Iyer, Aditya, Roeters, Steven J., Kogan, Vladimir, Woutersen, Sander, Claessens, Mireille M. A. E, Subramaniam, Vinod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668890/
https://www.ncbi.nlm.nih.gov/pubmed/28968082
http://dx.doi.org/10.1021/jacs.7b07403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668890/
https://www.ncbi.nlm.nih.gov/pubmed/28968082
http://dx.doi.org/10.1021/jacs.7b07403

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