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Metabolic remodeling in human colorectal cancer and surrounding tissues: alterations in regulation of mitochondrial respiration and metabolic fluxes

The aim of the work was to evaluate whether or not there is glycolytic reprogramming in the neighboring cells of colorectal cancer (CRC). Using postoperative material we have compared the functional capacity of oxidative phosphorylation (OXPHOS) in CRC cells, their glycolytic activity and their incl...

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Detalles Bibliográficos
Autores principales: Chekulayev, Vladimir, Mado, Kati, Shevchuk, Igor, Koit, Andre, Kaldma, Andrus, Klepinin, Aleksandr, Timohhina, Natalja, Tepp, Kersti, Kandashvili, Manana, Ounpuu, Lyudmila, Heck, Karoliina, Truu, Laura, Planken, Anu, Valvere, Vahur, Kaambre, Tuuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668899/
https://www.ncbi.nlm.nih.gov/pubmed/29124194
http://dx.doi.org/10.1016/j.bbrep.2015.08.020