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Enzymatic attributes of an l-isoaspartyl methyltransferase from Candida utilis and its role in cell survival

BACKGROUNDS: Spontaneous deamidation and isoaspartate (IsoAsp) formation contributes to aging and reduced longevity in cells. A protein-l-isoaspartate (d-aspartate) O-methyltransferase (PCMT) is responsible for minimizing IsoAsp moieties in most organisms. METHODS: PCMT was purified in its native fo...

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Detalles Bibliográficos
Autores principales: Banerjee, Shakri, Dutta, Trina, Lahiri, Sagar, Sengupta, Shinjinee, Gangopadhyay, Anushila, Kumar Karri, Suresh, Chakraborty, Sandeep, Bhattacharya, Debasish, Ghosh, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668901/
https://www.ncbi.nlm.nih.gov/pubmed/29124188
http://dx.doi.org/10.1016/j.bbrep.2015.08.015