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Enzymatic attributes of an l-isoaspartyl methyltransferase from Candida utilis and its role in cell survival
BACKGROUNDS: Spontaneous deamidation and isoaspartate (IsoAsp) formation contributes to aging and reduced longevity in cells. A protein-l-isoaspartate (d-aspartate) O-methyltransferase (PCMT) is responsible for minimizing IsoAsp moieties in most organisms. METHODS: PCMT was purified in its native fo...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668901/ https://www.ncbi.nlm.nih.gov/pubmed/29124188 http://dx.doi.org/10.1016/j.bbrep.2015.08.015 |