The leukotriene B(4) receptor BLT1 is stabilized by transmembrane helix capping mutations

In this study, we introduced structure-based rational mutations in the guinea pig leukotriene B(4) receptor (gpBLT1) in order to enhance the stabilization of the protein. Elements thought to be unfavorable for the stability of gpBLT1 were extracted based on the stabilization elements established in...

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Detalles Bibliográficos
Autores principales: Hori, Tetsuya, Nakamura, Motonao, Yokomizo, Takehiko, Shimizu, Takao, Miyano, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668910/
https://www.ncbi.nlm.nih.gov/pubmed/29124210
http://dx.doi.org/10.1016/j.bbrep.2015.09.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668910/
https://www.ncbi.nlm.nih.gov/pubmed/29124210
http://dx.doi.org/10.1016/j.bbrep.2015.09.007

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