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Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons

The stochastic dynamics and regulatory mechanisms that govern differentiation of individual human neural precursor cells (NPC) into mature neurons are currently not fully understood. Here, we used single-cell RNA-sequencing (scRNA-seq) of developing neurons to dissect/identify NPC subtypes and criti...

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Detalles Bibliográficos
Autores principales: Wang, Jiaxu, Jenjaroenpun, Piroon, Bhinge, Akshay, Angarica, Vladimir Espinosa, Del Sol, Antonio, Nookaew, Intawat, Kuznetsov, Vladimir A., Stanton, Lawrence W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668937/
https://www.ncbi.nlm.nih.gov/pubmed/29030469
http://dx.doi.org/10.1101/gr.223313.117