Quantifying the regulatory effect size of cis-acting genetic variation using allelic fold change

Mapping cis-acting expression quantitative trait loci (cis-eQTL) has become a popular approach for characterizing proximal genetic regulatory variants. In this paper, we describe and characterize log allelic fold change (aFC), the magnitude of expression change associated with a given genetic varian...

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Detalles Bibliográficos
Autores principales: Mohammadi, Pejman, Castel, Stephane E., Brown, Andrew A., Lappalainen, Tuuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668944/
https://www.ncbi.nlm.nih.gov/pubmed/29021289
http://dx.doi.org/10.1101/gr.216747.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668944/
https://www.ncbi.nlm.nih.gov/pubmed/29021289
http://dx.doi.org/10.1101/gr.216747.116

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