TGF-β1-induced epithelial–mesenchymal transition in lung cancer cells involves upregulation of miR-9 and downregulation of its target, E-cadherin

BACKGROUND: TGF-β1 plays an important role in the epithelial–mesenchymal transition (EMT) of epithelial cancers, including non-small cell lung cancer (NSCLC). While the full underlying mechanism remains unclear, miR-9 is known to play a critical role in the regulation of NSCLC cell invasion. We test...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Wu, Qian, Zhang, Ying, Zhang, Hua-Nan, Wang, Yong-Bin, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668967/
https://www.ncbi.nlm.nih.gov/pubmed/29118814
http://dx.doi.org/10.1186/s11658-017-0053-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668967/
https://www.ncbi.nlm.nih.gov/pubmed/29118814
http://dx.doi.org/10.1186/s11658-017-0053-1

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