The analgesic effects of triptolide in the bone cancer pain rats via inhibiting the upregulation of HDACs in spinal glial cells

BACKGROUND: Bone cancer pain (BCP) severely compromises the quality of life, while current treatments are still unsatisfactory. Here, we tested the antinociceptive effects of triptolide (T10), a substance with considerable anti-tumor efficacies on BCP, and investigated the underlying mechanisms targ...

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Detalles Bibliográficos
Autores principales: Hu, Xiao-Fan, He, Xiao-Tao, Zhou, Kai-Xiang, Zhang, Chen, Zhao, Wen-Jun, Zhang, Ting, Li, Jin-Lian, Deng, Jian-Ping, Dong, Yu-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668986/
https://www.ncbi.nlm.nih.gov/pubmed/29096654
http://dx.doi.org/10.1186/s12974-017-0988-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668986/
https://www.ncbi.nlm.nih.gov/pubmed/29096654
http://dx.doi.org/10.1186/s12974-017-0988-1

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