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The analgesic effects of triptolide in the bone cancer pain rats via inhibiting the upregulation of HDACs in spinal glial cells

BACKGROUND: Bone cancer pain (BCP) severely compromises the quality of life, while current treatments are still unsatisfactory. Here, we tested the antinociceptive effects of triptolide (T10), a substance with considerable anti-tumor efficacies on BCP, and investigated the underlying mechanisms targ...

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Detalles Bibliográficos
Autores principales:	Hu, Xiao-Fan, He, Xiao-Tao, Zhou, Kai-Xiang, Zhang, Chen, Zhao, Wen-Jun, Zhang, Ting, Li, Jin-Lian, Deng, Jian-Ping, Dong, Yu-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668986/ https://www.ncbi.nlm.nih.gov/pubmed/29096654 http://dx.doi.org/10.1186/s12974-017-0988-1

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