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Regulatory and evolutionary signatures of sex-biased genes on both the X chromosome and the autosomes

BACKGROUND: Sex is an important but understudied factor in the genetics of human diseases. Analyses using a combination of gene expression data, ENCODE data, and evolutionary data of sex-biased gene expression in human tissues can give insight into the regulatory and evolutionary forces acting on se...

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Detalles Bibliográficos
Autores principales: Shen, Jiangshan J., Wang, Ting-You, Yang, Wanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668987/
https://www.ncbi.nlm.nih.gov/pubmed/29096703
http://dx.doi.org/10.1186/s13293-017-0156-4