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Folic acid prevents cardiac dysfunction and reduces myocardial fibrosis in a mouse model of high-fat diet-induced obesity

BACKGROUND: Folic acid (FA) is an antioxidant that can reduce reactive oxygen species generation and can blunt cardiac dysfunction during ischemia. We hypothesized that FA supplementation prevents cardiac fibrosis and cardiac dysfunction induced by obesity. METHODS: Six-week-old C57BL6/J mice were f...

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Detalles Bibliográficos
Autores principales: Li, Wei, Tang, Renqiao, Ouyang, Shengrong, Ma, Feifei, Liu, Zhuo, Wu, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668988/
https://www.ncbi.nlm.nih.gov/pubmed/29118818
http://dx.doi.org/10.1186/s12986-017-0224-0