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Folic acid prevents cardiac dysfunction and reduces myocardial fibrosis in a mouse model of high-fat diet-induced obesity
BACKGROUND: Folic acid (FA) is an antioxidant that can reduce reactive oxygen species generation and can blunt cardiac dysfunction during ischemia. We hypothesized that FA supplementation prevents cardiac fibrosis and cardiac dysfunction induced by obesity. METHODS: Six-week-old C57BL6/J mice were f...
Autores principales: | Li, Wei, Tang, Renqiao, Ouyang, Shengrong, Ma, Feifei, Liu, Zhuo, Wu, Jianxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668988/ https://www.ncbi.nlm.nih.gov/pubmed/29118818 http://dx.doi.org/10.1186/s12986-017-0224-0 |
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