Cargando…

Tissue-engineered smooth muscle cell and endothelial progenitor cell bi-level cell sheets prevent progression of cardiac dysfunction, microvascular dysfunction, and interstitial fibrosis in a rodent model of type 1 diabetes-induced cardiomyopathy

BACKGROUND: Diabetes mellitus is a risk factor for coronary artery disease and diabetic cardiomyopathy, and adversely impacts outcomes following coronary artery bypass grafting. Current treatments focus on macro-revascularization and neglect the microvascular disease typical of diabetes mellitus-ind...

Descripción completa

Detalles Bibliográficos
Autores principales: Kawamura, Masashi, Paulsen, Michael J., Goldstone, Andrew B., Shudo, Yasuhiro, Wang, Hanjay, Steele, Amanda N., Stapleton, Lyndsay M., Edwards, Bryan B., Eskandari, Anahita, Truong, Vi N., Jaatinen, Kevin J., Ingason, Arnar B., Miyagawa, Shigeru, Sawa, Yoshiki, Woo, Y. Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668999/
https://www.ncbi.nlm.nih.gov/pubmed/29096622
http://dx.doi.org/10.1186/s12933-017-0625-4