Cargando…
Inhibition of DAMP signaling as an effective adjunctive treatment strategy in pneumococcal meningitis
BACKGROUND: Pneumococcal meningitis remains a potentially lethal and debilitating disease, mainly due to brain damage from sustained inflammation. The release of danger-associated molecular patterns (DAMPs), like myeloid-related protein 14 (MRP14) and high mobility group box 1 protein (HMGB1), plays...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669003/ https://www.ncbi.nlm.nih.gov/pubmed/29096648 http://dx.doi.org/10.1186/s12974-017-0989-0 |