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Targeting of Extracellular RNA Reduces Edema Formation and Infarct Size and Improves Survival After Myocardial Infarction in Mice

BACKGROUND: Following myocardial infarction (MI), peri‐infarct myocardial edema formation further impairs cardiac function. Extracellular RNA (eRNA) released from injured cells strongly increases vascular permeability. This study aimed to assess the role of eRNA in MI‐induced cardiac edema formation...

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Detalles Bibliográficos
Autores principales: Stieger, Philipp, Daniel, Jan‐Marcus, Thölen, Christiane, Dutzmann, Jochen, Knöpp, Kai, Gündüz, Dursun, Aslam, Muhammad, Kampschulte, Marian, Langheinrich, Alexander, Fischer, Silvia, Cabrera‐Fuentes, Hector, Wang, Yong, Wollert, Kai C., Bauersachs, Johann, Braun‐Dullaeus, Rüdiger, Preissner, Klaus T., Sedding, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669142/
https://www.ncbi.nlm.nih.gov/pubmed/28637776
http://dx.doi.org/10.1161/JAHA.116.004541