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SCN5A Genetic Polymorphisms Associated With Increased Defibrillator Shocks in Brugada Syndrome

BACKGROUND: Brugada syndrome (BrS) is an inherited primary arrhythmia disorder leading to sudden cardiac arrest. SCN5A, encoding the α‐subunit of the cardiac sodium channel (Nav1.5), is the most common pathogenic gene of BrS. An implantable cardioverter defibrillator (ICD) is the standard treatment...

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Detalles Bibliográficos
Autores principales: Makarawate, Pattarapong, Chaosuwannakit, Narumol, Vannaprasaht, Suda, Sahasthas, Dujdao, Koo, Seok Hwee, Lee, Edmund Jon Deoon, Tassaneeyakul, Wichittra, Barajas‐Martinez, Hector, Hu, Dan, Sawanyawisuth, Kittisak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669154/
https://www.ncbi.nlm.nih.gov/pubmed/28584071
http://dx.doi.org/10.1161/JAHA.116.005009