Fluorine teams up with water to restore inhibitor activity to mutant BPTI

Introducing fluorine into molecules has a wide range of effects on their physicochemical properties, often desirable but in most cases unpredictable. The fluorine atom imparts the C–F bond with low polarizability and high polarity, and significantly affects the behavior of neighboring functional gro...

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Detalles Bibliográficos
Autores principales: Ye, Shijie, Loll, Bernhard, Berger, Allison Ann, Mülow, Ulrike, Alings, Claudia, Wahl, Markus Christian, Koksch, Beate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669249/
https://www.ncbi.nlm.nih.gov/pubmed/29449928
http://dx.doi.org/10.1039/c4sc03227f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669249/
https://www.ncbi.nlm.nih.gov/pubmed/29449928
http://dx.doi.org/10.1039/c4sc03227f

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