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Photocontrol of the GTPase activity of the small G protein K-Ras by using an azobenzene derivative

The small G protein Ras is a central regulator of cellular signal transduction processes, functioning as a molecular switch. Switch mechanisms utilizing conformational changes in nucleotide-binding motifs have been well studied at the molecular level. Azobenzene is a photochromic molecule that under...

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Detalles Bibliográficos
Autores principales: Iwata, Seigo, Maruta, Shinsaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669354/
https://www.ncbi.nlm.nih.gov/pubmed/29124213
http://dx.doi.org/10.1016/j.bbrep.2015.10.002