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Photocontrol of the GTPase activity of the small G protein K-Ras by using an azobenzene derivative
The small G protein Ras is a central regulator of cellular signal transduction processes, functioning as a molecular switch. Switch mechanisms utilizing conformational changes in nucleotide-binding motifs have been well studied at the molecular level. Azobenzene is a photochromic molecule that under...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669354/ https://www.ncbi.nlm.nih.gov/pubmed/29124213 http://dx.doi.org/10.1016/j.bbrep.2015.10.002 |