Salbutamol inhibits ubiquitin-mediated survival motor neuron protein degradation in spinal muscular atrophy cells

Spinal muscular atrophy (SMA) is a common autosomal recessive neuromuscular disorder that is currently incurable. SMA is caused by decreased levels of the survival motor neuron protein (SMN), as a result of loss or mutation of SMN1. Although the SMN1 homolog SMN2 also produces some SMN protein, it d...

Descripción completa

Detalles Bibliográficos
Autores principales: Harahap, Nur Imma Fatimah, Nurputra, Dian Kesumapramudya, Ar Rochmah, Mawaddah, Shima, Ai, Morisada, Naoya, Takarada, Toru, Takeuchi, Atsuko, Tohyama, Yumi, Yanagisawa, Shinichiro, Nishio, Hisahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669398/
https://www.ncbi.nlm.nih.gov/pubmed/29124224
http://dx.doi.org/10.1016/j.bbrep.2015.10.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669398/
https://www.ncbi.nlm.nih.gov/pubmed/29124224
http://dx.doi.org/10.1016/j.bbrep.2015.10.012

Ejemplares similares