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Novel curcumin derivatives as potent inhibitors of amyloid β aggregation

Modulation of abnormal amyloid β (Aβ) aggregation is considered to be a potential therapeutic target for Alzheimer’s disease (AD). Recent in vitro and in vivo experiments suggest that inhibition of Aβ aggregation by curcumin would exert favorable effects for preventing or treating AD. We have previo...

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Detalles Bibliográficos
Autores principales: Yanagisawa, Daijiro, Taguchi, Hiroyasu, Morikawa, Shigehiro, Kato, Tomoko, Hirao, Koichi, Shirai, Nobuaki, Tooyama, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669405/
https://www.ncbi.nlm.nih.gov/pubmed/29124225
http://dx.doi.org/10.1016/j.bbrep.2015.10.009