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Using long ssDNA polynucleotides to amplify STRs loci in degraded DNA samples

Obtaining informative short tandem repeat (STR) profiles from degraded DNA samples is a challenging task usually undermined by locus or allele dropouts and peak-high imbalances observed in capillary electrophoresis (CE) electropherograms, especially for those markers with large amplicon sizes. We he...

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Detalles Bibliográficos
Autores principales: Mautner, Martín E., Pérez Santángelo, Agustín, Corti Bielsa, Rodrigo M., Sala, Andrea, Ginart, Santiago, Corach, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669423/
https://www.ncbi.nlm.nih.gov/pubmed/29099837
http://dx.doi.org/10.1371/journal.pone.0187190