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Using long ssDNA polynucleotides to amplify STRs loci in degraded DNA samples
Obtaining informative short tandem repeat (STR) profiles from degraded DNA samples is a challenging task usually undermined by locus or allele dropouts and peak-high imbalances observed in capillary electrophoresis (CE) electropherograms, especially for those markers with large amplicon sizes. We he...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669423/ https://www.ncbi.nlm.nih.gov/pubmed/29099837 http://dx.doi.org/10.1371/journal.pone.0187190 |