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Tetracyclines downregulate the production of LPS-induced cytokines and chemokines in THP-1 cells via ERK, p38, and nuclear factor-κB signaling pathways

Recent reports have shown that antibiotics such as macrolide, aminoglycoside, and tetracyclines have immunomodulatory effects in addition to essential antibiotic effects. These agents may have important effects on the regulation of cytokine and chemokine production. However, the precise mechanism is...

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Detalles Bibliográficos
Autores principales: Sun, Jian, Shigemi, Hiroko, Tanaka, Yukie, Yamauchi, Takahiro, Ueda, Takanori, Iwasaki, Hiromichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669446/
https://www.ncbi.nlm.nih.gov/pubmed/29124230
http://dx.doi.org/10.1016/j.bbrep.2015.11.003