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Tetracyclines downregulate the production of LPS-induced cytokines and chemokines in THP-1 cells via ERK, p38, and nuclear factor-κB signaling pathways
Recent reports have shown that antibiotics such as macrolide, aminoglycoside, and tetracyclines have immunomodulatory effects in addition to essential antibiotic effects. These agents may have important effects on the regulation of cytokine and chemokine production. However, the precise mechanism is...
Autores principales: | Sun, Jian, Shigemi, Hiroko, Tanaka, Yukie, Yamauchi, Takahiro, Ueda, Takanori, Iwasaki, Hiromichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669446/ https://www.ncbi.nlm.nih.gov/pubmed/29124230 http://dx.doi.org/10.1016/j.bbrep.2015.11.003 |
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