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Relief of endoplasmic reticulum stress enhances DNA damage repair and improves development of pre-implantation embryos

Early-cleaving embryos are known to have better capacity to reach the blastocyst stage and produce better quality embryos compared to late-cleaving embryos. To investigate the significance of endoplasmic reticulum (ER) stress on early embryo cleavage kinetics and development, porcine embryos produce...

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Detalles Bibliográficos
Autores principales: Dicks, Naomi, Bohrer, Rodrigo C., Gutierrez, Karina, Michalak, Marek, Agellon, Luis B., Bordignon, Vilceu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669469/
https://www.ncbi.nlm.nih.gov/pubmed/29099865
http://dx.doi.org/10.1371/journal.pone.0187717