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Mechanism of activation at the selectivity filter of the KcsA K(+) channel

Potassium channels are opened by ligands and/or membrane potential. In voltage-gated K(+) channels and the prokaryotic KcsA channel, conduction is believed to result from opening of an intracellular constriction that prevents ion entry into the pore. On the other hand, numerous ligand-gated K(+) cha...

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Detalles Bibliográficos
Autores principales: Heer, Florian T, Posson, David J, Wojtas-Niziurski, Wojciech, Nimigean, Crina M, Bernèche, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669632/
https://www.ncbi.nlm.nih.gov/pubmed/28994652
http://dx.doi.org/10.7554/eLife.25844