Tailored nanostructured platforms for boosting transcorneal permeation: Box–Behnken statistical optimization, comprehensive in vitro, ex vivo and in vivo characterization

Ocular drug delivery systems suffer from rapid drainage, intractable corneal permeation and short dosing intervals. Transcorneal drug permeation could increase the drug availability and efficiency in the aqueous humor. The aim of this study was to develop and optimize nanostructured formulations to...

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Detalles Bibliográficos
Autores principales: Elsayed, Ibrahim, Sayed, Sinar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669792/
https://www.ncbi.nlm.nih.gov/pubmed/29133980
http://dx.doi.org/10.2147/IJN.S150366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669792/
https://www.ncbi.nlm.nih.gov/pubmed/29133980
http://dx.doi.org/10.2147/IJN.S150366

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