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A native-like bispecific antibody suppresses the inflammatory cytokine response by simultaneously neutralizing tumor necrosis factor-alpha and interleukin-17A

Anti-tumor necrosis factor (TNF) therapies are successful in the treatment of inflammatory disorders. However, some patients with rheumatoid arthritis (RA) fail to response anti-TNF drugs due to the compensation of other inflammatory signals. In this study, to reduce compensatory responses of interl...

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Detalles Bibliográficos
Autores principales: Xu, Tianshu, Ying, Tianlei, Wang, Lili, Zhang, Xiaohua Douglas, Wang, Ying, Kang, Lishan, Huang, Tao, Cheng, Liang, Wang, Liping, Zhao, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669854/
https://www.ncbi.nlm.nih.gov/pubmed/29137228
http://dx.doi.org/10.18632/oncotarget.19899