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A native-like bispecific antibody suppresses the inflammatory cytokine response by simultaneously neutralizing tumor necrosis factor-alpha and interleukin-17A
Anti-tumor necrosis factor (TNF) therapies are successful in the treatment of inflammatory disorders. However, some patients with rheumatoid arthritis (RA) fail to response anti-TNF drugs due to the compensation of other inflammatory signals. In this study, to reduce compensatory responses of interl...
Autores principales: | Xu, Tianshu, Ying, Tianlei, Wang, Lili, Zhang, Xiaohua Douglas, Wang, Ying, Kang, Lishan, Huang, Tao, Cheng, Liang, Wang, Liping, Zhao, Qi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669854/ https://www.ncbi.nlm.nih.gov/pubmed/29137228 http://dx.doi.org/10.18632/oncotarget.19899 |
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