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The nucleocytoplasmic translocation and up-regulation of ING5 protein in breast cancer: a potential target for gene therapy

Here, we found that ING5 overexpression resulted in a lower proliferation, reduced glucose metabolism, S arrest, decreased migration and invasion, apoptotic induction, fat accumulation, autophagy, senescence and mesenchymal-epithelial–transition of breast cancer cells. It also suppressed the tumor g...

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Detalles Bibliográficos
Autores principales: Ding, Xiao-Qing, Zhao, Shuang, Yang, Lei, Zhao, Xin, Zhao, Gui-Feng, Zhao, Shu-Peng, Li, Zhi-Jie, Zheng, Hua-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669862/
https://www.ncbi.nlm.nih.gov/pubmed/29137236
http://dx.doi.org/10.18632/oncotarget.17918