Immune profiling of NF1-associated tumors reveals histologic subtype distinctions and heterogeneity: implications for immunotherapy

Successful treatment of neurofibromatosis type 1 (NF1)-associated tumors poses a significant clinical challenge. While the primary underlying genetic defect driving RAS signaling is well described, recent evidence suggests immune dysfunction contributes to tumor pathogenesis and malignant transforma...

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Detalles Bibliográficos
Autores principales: Haworth, Kellie B., Arnold, Michael A., Pierson, Christopher R., Choi, Kwangmin, Yeager, Nicholas D., Ratner, Nancy, Roberts, Ryan D., Finlay, Jonathan L., Cripe, Timothy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669868/
https://www.ncbi.nlm.nih.gov/pubmed/29137242
http://dx.doi.org/10.18632/oncotarget.18301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669868/
https://www.ncbi.nlm.nih.gov/pubmed/29137242
http://dx.doi.org/10.18632/oncotarget.18301

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