Understanding the mechanism of binding between Gab2 and the C terminal SH3 domain from Grb2

Gab2 is a large disordered protein that regulates several cellular signalling pathways and is overexpressed in different forms of cancer. Because of its disordered nature, a detailed characterization of the mechanisms of recognition between Gab2 and its physiological partners is particularly difficu...

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Detalles Bibliográficos
Autores principales: Toto, Angelo, Bonetti, Daniela, De Simone, Alfonso, Gianni, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669894/
https://www.ncbi.nlm.nih.gov/pubmed/29137268
http://dx.doi.org/10.18632/oncotarget.19323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669894/
https://www.ncbi.nlm.nih.gov/pubmed/29137268
http://dx.doi.org/10.18632/oncotarget.19323

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