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Understanding the mechanism of binding between Gab2 and the C terminal SH3 domain from Grb2
Gab2 is a large disordered protein that regulates several cellular signalling pathways and is overexpressed in different forms of cancer. Because of its disordered nature, a detailed characterization of the mechanisms of recognition between Gab2 and its physiological partners is particularly difficu...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669894/ https://www.ncbi.nlm.nih.gov/pubmed/29137268 http://dx.doi.org/10.18632/oncotarget.19323 |