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Implications of mutational spectrum in myelodysplastic syndromes based on targeted next-generation sequencing

Myelodysplastic syndromes (MDS) are a group of myeloid hematological malignancies, with a high risk of progression to acute myeloid leukemia (AML). To explore the role of acquired mutations in MDS, 111 MDS-associated genes were screened using next-generation sequencing (NGS), in 125 patients. One or...

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Detalles Bibliográficos
Autores principales: Xu, Yuanyuan, Li, Yan, Xu, Qingyu, Chen, Yuelong, Lv, Na, Jing, Yu, Dou, Liping, Bo, Jian, Hou, Guangyuan, Guo, Jing, Wang, Xiuli, Wang, Lili, Li, Yonghui, Chen, Chongjian, Yu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669905/
https://www.ncbi.nlm.nih.gov/pubmed/29137279
http://dx.doi.org/10.18632/oncotarget.19628