Cargando…
Implications of mutational spectrum in myelodysplastic syndromes based on targeted next-generation sequencing
Myelodysplastic syndromes (MDS) are a group of myeloid hematological malignancies, with a high risk of progression to acute myeloid leukemia (AML). To explore the role of acquired mutations in MDS, 111 MDS-associated genes were screened using next-generation sequencing (NGS), in 125 patients. One or...
Autores principales: | Xu, Yuanyuan, Li, Yan, Xu, Qingyu, Chen, Yuelong, Lv, Na, Jing, Yu, Dou, Liping, Bo, Jian, Hou, Guangyuan, Guo, Jing, Wang, Xiuli, Wang, Lili, Li, Yonghui, Chen, Chongjian, Yu, Li |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669905/ https://www.ncbi.nlm.nih.gov/pubmed/29137279 http://dx.doi.org/10.18632/oncotarget.19628 |
Ejemplares similares
-
Mutational spectrum and risk stratification of intermediate-risk acute myeloid leukemia patients based on next-generation sequencing
por: Wang, Bianhong, et al.
Publicado: (2016) -
Clinical implications of genome-wide DNA methylation studies in acute myeloid leukemia
por: Li, Yan, et al.
Publicado: (2017) -
Detection of prognostic methylation markers by methylC-capture sequencing in acute myeloid leukemia
por: Li, Yan, et al.
Publicado: (2017) -
Clinical implications of the quantitative detection of ID4 gene methylation in myelodysplastic syndrome
por: Kang, Huiyuan, et al.
Publicado: (2015) -
Methylation-associated silencing of BASP1 contributes to leukemogenesis in t(8;21) acute myeloid leukemia
por: Zhou, Lei, et al.
Publicado: (2018)