Early detection of thymidylate synthase resistance in non-small cell lung cancer with FLT-PET imaging

INTRODUCTION: Inhibition of thymidylate synthase (TS) results in a transient compensatory “flare” in thymidine salvage pathway activity measureable with (18)F-thymidine (FLT)- positron emission tomography (PET) at 2hrs. of therapy which may predict non-small cell lung cancer (NSCLC) sensitivity to T...

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Detalles Bibliográficos
Autores principales: Chen, Xiao, Yang, Yizeng, Katz, Sharyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669922/
https://www.ncbi.nlm.nih.gov/pubmed/29137296
http://dx.doi.org/10.18632/oncotarget.19751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669922/
https://www.ncbi.nlm.nih.gov/pubmed/29137296
http://dx.doi.org/10.18632/oncotarget.19751

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