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Early detection of thymidylate synthase resistance in non-small cell lung cancer with FLT-PET imaging

INTRODUCTION: Inhibition of thymidylate synthase (TS) results in a transient compensatory “flare” in thymidine salvage pathway activity measureable with (18)F-thymidine (FLT)- positron emission tomography (PET) at 2hrs. of therapy which may predict non-small cell lung cancer (NSCLC) sensitivity to T...

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Detalles Bibliográficos
Autores principales:	Chen, Xiao, Yang, Yizeng, Katz, Sharyn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669922/ https://www.ncbi.nlm.nih.gov/pubmed/29137296 http://dx.doi.org/10.18632/oncotarget.19751

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