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Monocarboxylate transporter 1 (MCT1), a tool to stratify acute myeloid leukemia (AML) patients and a vehicle to kill cancer cells

Dysregulation of glucose/lactate dynamics plays a role in cancer progression, and MCTs are key elements in metabolic remodeling. VEGF is a relevant growth factor in the maintenance of bone marrow microenvironment and it is also important in hematological diseases. Our aim was to investigate the role...

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Detalles Bibliográficos
Autores principales: Lopes-Coelho, Filipa, Nunes, Carolina, Gouveia-Fernandes, Sofia, Rosas, Rita, Silva, Fernanda, Gameiro, Paula, Carvalho, Tânia, Gomes da Silva, Maria, Cabeçadas, José, Dias, Sérgio, Gonçalves, Luís G., Serpa, Jacinta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669930/
https://www.ncbi.nlm.nih.gov/pubmed/29137304
http://dx.doi.org/10.18632/oncotarget.20294