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RLIM suppresses hepatocellular carcinogenesis by up-regulating p15 and p21

Hepatocellular carcinogenesis results from dysregulation of oncogenes and tumor suppressors that influence cellular proliferation, differentiation and apoptosis. p15 and p21 are cyclin-dependent kinase inhibitors, which arrest cell proliferation and serve as critical tumor suppressors. Here we repor...

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Detalles Bibliográficos
Autores principales: Huang, Yongsheng, Nie, Meng, Li, Chuang, Zhao, Yingjie, Li, Jiahui, Zhou, Lan, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669951/
https://www.ncbi.nlm.nih.gov/pubmed/29137325
http://dx.doi.org/10.18632/oncotarget.20904