Virtual screening approach to identifying influenza virus neuraminidase inhibitors using molecular docking combined with machine-learning-based scoring function

In recent years, an epidemic of the highly pathogenic avian influenza H7N9 virus has persisted in China, with a high mortality rate. To develop novel anti-influenza therapies, we have constructed a machine-learning-based scoring function (RF-NA-Score) for the effective virtual screening of lead comp...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Ai, Hai-Xin, Li, Shi-Meng, Qi, Meng-Yuan, Zhao, Jian, Zhao, Qi, Liu, Hong-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669956/
https://www.ncbi.nlm.nih.gov/pubmed/29137330
http://dx.doi.org/10.18632/oncotarget.20915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669956/
https://www.ncbi.nlm.nih.gov/pubmed/29137330
http://dx.doi.org/10.18632/oncotarget.20915

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