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Long noncoding RNA XIST is a prognostic factor in colorectal cancer and inhibits 5-fluorouracil-induced cell cytotoxicity through promoting thymidylate synthase expression

A major reason for the failure of advanced colorectal cancer (CRC) treatment is the occurrence of chemoresistance to 5-fluorouracil (5FU)-based treatment. Recent studies have shown that long non-coding RNAs (lncRNAs) are critical regulators in chemoresistance. By using the next generation HiSeq sequ...

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Detalles Bibliográficos
Autores principales: Xiao, Yang, Yurievich, Usenko Alexander, Yosypovych, Smorzhevskyi Valentyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669958/
https://www.ncbi.nlm.nih.gov/pubmed/29137332
http://dx.doi.org/10.18632/oncotarget.20487