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The coffee diterpene kahweol enhances sensitivity to sorafenib in human renal carcinoma Caki cells through down-regulation of Mcl-1 and c-FLIP expression

Sorafenib is approved for the treatment of hepatocellular carcinoma (HCC) and advanced renal cell carcinoma (RCC). However, low tumor response and side effects have been widely reported. Therefore, to improve the efficacy of sorafenib, we investigated whether combined treatment with sorafenib and ka...

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Detalles Bibliográficos
Autores principales: Min, Kyoung-Jin, Um, Hee Jung, Kim, Jee In, Kwon, Taeg Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669960/
https://www.ncbi.nlm.nih.gov/pubmed/29137334
http://dx.doi.org/10.18632/oncotarget.20541