Inhibition of cell cycle progression by the hydroxytyrosol–cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells

Hydroxytyrosol (HT), a polyphenol of olive oil, downregulates epidermal growth factor (EGFR) expression and inhibits cell proliferation in colon cancer (CC) cells, with mechanisms similar to that activated by the EGFR inhibitor, cetuximab. Here, we studied whether HT treatment would enhance the cetu...

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Detalles Bibliográficos
Autores principales: Terzuoli, Erika, Nannelli, Ginevra, Frosini, Maria, Giachetti, Antonio, Ziche, Marina, Donnini, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669961/
https://www.ncbi.nlm.nih.gov/pubmed/29137335
http://dx.doi.org/10.18632/oncotarget.20544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669961/
https://www.ncbi.nlm.nih.gov/pubmed/29137335
http://dx.doi.org/10.18632/oncotarget.20544

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