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Clinicopathological significance of the p16 hypermethylation in multiple myeloma, a systematic review and meta-analysis

It is well known that the loss of function of the p16INK4A gene is mainly caused by the hypermethylation of the p16 gene; however, whether or not the inactivation is associated with the clinical significance of multiple myeloma (MM) remains elusive. A meta-analysis was conducted to quantitatively de...

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Detalles Bibliográficos
Autores principales: Yu, Huiqing, Yang, Liejun, Fu, Yunfeng, Gao, Meng, Tian, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669967/
https://www.ncbi.nlm.nih.gov/pubmed/29137341
http://dx.doi.org/10.18632/oncotarget.18742