Pharmacologic Inhibition of β-Catenin With Pyrvinium Inhibits Murine and Human Models of Wilms Tumor

Wilms tumor (WT) is the most common renal malignancy in children and the fourth most common pediatric solid malignancy in the US. Although the mechanisms underlying the WT biology are complex, these tumors most often demonstrate activation of the canonical Wnt/β-catenin pathway. We and others have s...

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Detalles Bibliográficos
Autores principales: Polosukhina, Dina, Love, Harold D., Moses, Harold L., Lee, Ethan, Zent, Roy, Clark, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670010/
https://www.ncbi.nlm.nih.gov/pubmed/28695795
http://dx.doi.org/10.3727/096504017X14992942781895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670010/
https://www.ncbi.nlm.nih.gov/pubmed/28695795
http://dx.doi.org/10.3727/096504017X14992942781895

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